Probiotics for Depressive Symptomatology and Neural Activity.
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-40
SponsorUniversity of Reading
About this trial
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
Eligibility criteria
Qualifiers
Mild to moderate depression symptoms (BDI-II 12-28)
Males and females
Age range will be 25-40 years
Right-handed participants only (required for EEG)
Disqualifiers
Taking antidepressants (up to 2 months prior to inclusion)
Undergoing psychological treatment in the form of counselling, therapy or similar (up to 1 month prior to inclusion)
Any diagnosed chronic medical condition (e.g. diabetes) or psychiatric illness.
Use of antibiotics or laxatives (up to 3 months prior to inclusion)
Trial design
Treatments tested in this trial
- Ecologic® Barrier
- Placebo powder
Treatment groups
76 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Reading
Lead sponsor
Winclove Probiotics B.V.
Collaborator
Source ClinicalTrials.gov