This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).
Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia.
American Society of Anesthesiologists Physical Status (ASA) score I-III.
Age range of 18-70 years.
Both male and female patients.
Emergency surgeries.
Uncontrolled hypertension (systolic blood pressure >150 mm Hg) despite medication.
Recent acute cardiovascular events, including heart failure or acute coronary syndrome.
Chronic kidney disease with a glomerular filtration rate <30 ml/min/1.73 m² or requiring renal replacement therapy.