Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorFondazione del Piemonte per l'Oncologia
About this trial
This multicenter randomized trial evaluates whether routine use of Progel Platinum surgical sealant on stapled fissure lines during VATS upper or lower lobectomy for NSCLC reduces pleural drainage duration compared with standard stapling alone. Secondary objectives include postoperative length of stay, incidence and duration of postoperative air leaks, residual pleural space, safety outcomes, and hospitalization costs.
Eligibility criteria
Qualifiers
Age ≥18 years
Written informed consent
Planned VATS upper or lower lobectomy for NSCLC
Minimally invasive thoracoscopic approach
Disqualifiers
Induction radiochemotherapy or chemo-immunotherapy
Severe COPD: GOLD 3 or higher
Sleeve resection or extended resection involving other lobes/chest wall/pericardium, etc.
Albumin intolerance/allergy
Trial design
Treatments tested in this trial
- Progel Platinum
- Mechanical Stapling
Treatment groups
160 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov