Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2026: Engagement-Focused GenAI-based Chatbot for Real-Time Smoking Cessation Support

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe University of Hong Kong

About this trial

The goal of this trial is to learn if chatbot-based instant messaging works to help smoking cessation in general adult smokers. It will also learn about the experience, attitude, and perception of using an LLM-based chatbot. The main questions it aims to answer are:

1. Will an engagement-focused LLM-based chatbot smoking cessation intervention have a non-inferior validated abstinence rate than the control group? 2. Will an LLM-based chatbot smoking cessation intervention have a non-inferior self-reported abstinence rate, smoking reduction rate, and smoking cessation services use rate than the control group?

Researchers will compare an LLM-based chatbot smoking-cessation intervention to a human-led instant messaging support group (brief advice based on AWARD and personalised active referral) to determine whether chatbot-based instant messaging support promotes smoking cessation.

Participants in the intervention group will receive:

1. AWARD advice 2. Personalised active referral 3. 12 weeks of chatbot-based instant messaging support (via WhatsApp)

Eligibility criteria

Qualifiers

Hong Kong residents aged 18 years or above

Smoke at least one cigarette (including heated tobacco products) per day or use an e-cigarette daily in the preceding 3 months

Able to communicate in Cantonese (including reading and writing Chinese)

Saliva cotinine level ≥30 ng/mL

Disqualifiers

Smokers who have communication barriers (either physical or cognitive)

Smokers who are currently participating in other smoking cessation programs or services

Trial design

Treatments tested in this trial

  • AWARD advice
  • Brief leaflet on health warning and smoking cessation
  • Referral card
  • Self-help smoking cessation booklet
  • Personalized active referral
  • 12 weeks of chatbot-based instant messaging support
  • 12 weeks of human-led instant messaging support
  • Reminder messages

Treatment groups

998 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The University of Hong Kong

Lead sponsor

Hong Kong Council on Smoking and Health

Collaborator