The goal of this prospective randomized crossover experimental study is to assess the effectiveness and tolerance of circular and flat fabric garments in stabilizing lower-limb volume in lipedema. It will assess the effectiveness of the garments and determine any differences between both types of hosiery currently used in routine clinical practice. Participants will be prescribed either circular or flat-knitted pantyhose and wear them daily for 6 months. After 6 months, they will change the type of garment.
Clinical diagnosis of lipedema: increased lowe-limb volume, disproportion between upper and lower body, and pain.
Lipedema type III stages 1 or 2.
Negative pitting sign.
In maintenance treatment phase with a class II circular-knitted compression garment for at least 6 months.
Lipedema with fatty lobulations.
Body Mass Index (BMI) ≥ 30 kg/m2.
Waist-to-Height Ratio > 0.53.
Pregnancy.
Isabel Forner-Cordero, MD, PhD
Lead sponsor
Instituto de Investigacion Sanitaria La Fe
Sponsor institution
Hospital Provincial de Castellon
Collaborator
Hospital Arnau de Vilanova
Collaborator