Prophylactic Anti-epileptic Regimen in Traumatic Brain Injury
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorAssiut University
About this trial
To evaluate the effectiveness and safety of anti-epileptic drugs in the prevention of early and late post-traumatic seizures among patients with trauma brain injury
Eligibility criteria
Qualifiers
Patients with a confirmed diagnosis of traumatic brain injury (clinical and/or radiological), including both surgical and conservative management
Admission within 24 hours of injury
Eligible for antiepileptic prophylaxis according to clinical guidelines
Written informed consent obtained.
Disqualifiers
Pre-existing epilepsy or seizure disorder.
Seizure episode before or during admission unrelated to acute TBI.
Prior use of antiepileptic drugs before admission.
Severe renal impairment (creatinine clearance <30 mL/min).
Trial design
Treatments tested in this trial
- Anti-Epileptic
Treatment groups
70 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov