Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMorten Ladekarl

About this trial

Proseq Cancer is a precision medicine program based on in-house whole exome sequencing (WES) and RNA sequencing. The approved protocol allows for biobanking, registration of clinical and laboratory data, and sharing of genomic data with the purpose of research, while fulfilling the Danish General Data Protection Regulation (GDPR) requirements. Patients are recruited from the North Denmark Region.

Treatment can be offered on site if a targeted drug of a nationally approved indication is suggested by the national tumor board (NTB). If not, the patient may be treated in an available clinical protocol. If no approved drug or relevant protocol is available or feasible, treatment with a targeted drug used outside a clinical protocol is pursued.

Eligibility criteria

Qualifiers

Incurable, progressing and/or life-threatening cancer

Expected residual survival of at least 3 months

No efficient remaining standard treatment options

Patient recruited from the Region of Northern Jutland, Denmark

Disqualifiers

WHO Performance Status >2

Significant comorbidity, concurrent medication or laboratory values imposing an unacceptable risk at medical oncological treatment

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

3,000 Participants
are grouped into 1 trial group

Sponsors and collaborators

Morten Ladekarl

Lead sponsor

Aalborg University Hospital

Sponsor institution