Prospective Cohort for Adult Hemophagocytosis
ConditionHemophagocytic Lymphohistiocytoses
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorSamsung Medical Center
About this trial
This prospective study enrolls subjects who have clinical and laboratory manifestations related with hemophagocytic lymphohistiocytosis. The purpose of the study is to evaluate clinical and biological features of adult hemophagocytic lymphohistiocytosis. The enrolled subjects into this study will be evaluated according to the HLH (hemophagocytic lymphohistiocytosis)criteria and treated with systemic immunosuppressive therapy or chemotherapy. All subjects will be regularly monitored by physicians participating in this study.
Eligibility criteria
Qualifiers
Subjects should fulfill the following criteria
Subjects should have at least one of the following problems
Presence of hemophagocytosis in tissue or bone marrow
Presence of at least 3 conditions among 8 conditions of HLH diagnostic criteria
Disqualifiers
Subjects cannot satisfy the inclusion criteria
Trial design
Treatments tested in this trial
- Steroids
- Etoposide
Treatment groups
81 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov