Intermittent theta-burst stimulation (iTBS), a variant of repetitive transcranial magnetic stimulation (rTMS), is a well-documented treatment for depression. The aim of this study is to evaluate the effectiveness of an accelerated iTBS protocol (1W-AiTBS) in routine clinical practice. In the accelerated protocol, patients receive 600 pulses per session, for a total of 30 sessions administered over 5-14 treatment days. Patient inclusion will take place over a maximum period of 1.5 years, with a maximum sample size of 150 patients. The target sample size is at least 36 patients. Patients will complete self-rating questionnaires at screening, before and after treatment, and at 6 weeks, 12 weeks, and 6 months from the first day of treatment.
diagnosis of depression verified through a Mini International Neuropsychiatric Interview (M.I.N.I.)
provision of signed informed consent form
indication for TMS is depression
conductive ferromagnetic or other metals implanted in the head or within 30 cm of the treatment coil
implanted device that is activated or controlled in any way by physiological signals
implanted mediation pumps
intracardiac lines, even when removed