The study objective is to evaluate the use of Stereotactic Body Radiotherapy (high dose of radiation in a few fractions) to cure primary renal cancer in those patients that are not indicated to surgery (high risk of complications, refusal of the patient). This therapy is already used in clinical setting for many tumors with good tolerance as it is not invasive, does not require anesthesia and hospitalization making it suitable for elderly people and frail patients. However there are not enough information regarding the use of ablative doses for the cure of renal cancer and for this reason this study aims to support the use of Stereotactic Body Radiotherapy as a standard of care for inoperable primary renal tumor. This is an observational study, so it collects data from clinical pratice only and does not request study specific procedures.
Age ≥ 18 years
ECOG performance status 0 - 2
Histologically confirmed diagnosis of primary RCC
cT1 stage tumor with single lesion with maximum diameter of 7 cm
Estimated glomerular filtration rate (eGFR) < 30 mls/min
Previous radiotherapy on the same site
Previous systemic therapy for RCC
Tumor diameter larger than 7 cm