Prostate Reirradiation Toxicity Outcomes Feasibility Study
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorUniversity of Leeds
About this trial
The RO-PIP trial aims to determine the feasibility of recruitment to a trial randomising patients to salvage ultra-hypofractionated external beam radiotherapy or high dose rate brachytherapy and provide prospective data on patient recorded toxicity outcomes that will inform a future phase III trial.
Eligibility criteria
Qualifiers
Male individuals aged over 18 years
Histologically confirmed locally recurrent prostate cancer (following previous radiotherapy no less than 2 years ago)
No metastatic disease
Able and willing to provide an informed consent to participate
Disqualifiers
Patients who are unfit for a general anaesthetic due to other comorbidities
Clinical or radiological evidence of metastatic prostate disease
Any patient with a medical or psychiatric condition that impairs their ability to give informed consent
Contraindication or intolerance of magnetic resonance scanning
Trial design
Treatments tested in this trial
- Brachytherapy
- Sterotactic Body Radiotherapy
Treatment groups
60 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov