The goal of this clinical trial is to to compare the prosthetic complication rate and Oral Health-Related Quality of Life (OHRQoL) between screw-retained monolithic zirconia frameworks and CNC-milled titanium frameworks with zirconia superstructures in completely edentulous patients restored with full-arch implant-supported prostheses over a follow-up period of 12 months.
Aged 18 years or older.
Able to understand the study procedures and provide written informed consent.
In good general health, classified as American Society of Anesthesiologists (ASA) Physical Status Class I or II.
Completely edentulous in the arch to be treated (maxilla and/or mandible).
Uncontrolled diabetes (HbA1c > 7.0%).
History of radiotherapy in the head and neck region.
History of intravenous bisphosphonate therapy.
Immunosuppressed or immunocompromised status.