Proving Utility of a New Field-cycling MRI Prototype in Acute Stroke Patients
ConditionStroke Acute
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Aberdeen
About this trial
The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can show changes in the brain within the first day of a stroke due to a blocked blood vessel or bleeding in the brain. The main question it aims to answer is:
• Can FCI identify brain tissue that might recover within the first few hours after a stroke begins?
Participants will undergo a standard MRI scan and an FCI scan, as soon as possible after hospital admission.
Participants who have had a blocked blood vessel will also provide a blood sample and will have a follow up visit at 30 days for repeat of both scans and providing another blood sample.
Eligibility criteria
Qualifiers
Acute stroke (<24 hours from symptom onset).
NIHSS ≥4 and <25 with cortical involvement and/or large vessel occlusion on baseline imaging.
Able to undergo 3T and FCI MRI <24h of onset.
With or without thrombolysis.
Disqualifiers
Contraindications to MRI.
Medically unstable.
Unable to comprehend or comply with instructions regarding scanning
Prior mRS of >3.
Trial design
Treatments tested in this trial
- 3T MRI research scan
- Field-Cycling Imaging research scan
- Follow up 3T MRI research scan
- Follow up Field-Cycling Imaging research scan
- Blood samples for clotting experiments in vitro
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Aberdeen
Lead sponsor
NHS Grampian
Collaborator
Source ClinicalTrials.gov