About this trial
Offspring of parents with bipolar disorder (BD) and schizophrenia (SZ) are vulnerable and at high risk for these disorders. Despite the fact that positive family history of SZ or BD is the strongest predictor for the development of these severe mental illnesses, there is limited evidence assessing young adults of SZ and BP simultaneously with lack of detailed handling of similarities in risk and developmental trajectories during adolescence
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
age <6 or >18 IQ < 70 .
Trial population
families with one or two parents with psychiatric disorder.
Trial design
Family-based
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Early recognition of psychiatric disorders among children and adolescents , So Early interventions to decrease the severity of the disorder can be done
Early recognition and intervention during the prodromal phase is still at an early stage in Sz \[12\] with limited research into valid prodromal criteria for BP \[13\]. Retrospective studies combining subjects with early-onset mania and early-onset first-episode psychosis have reported a similar pattern of neurodevelopmental and psychopathological features predating the appearance of more specific prodromal symptoms in both disorders \[14, 15\]. Therefore, the substantial overlap of symptoms in the initial phases suggests that early identification programmes should be aimed at detecting both the pre-psychotic and the pre-manic phases of SZ and BP \[16\].
Secondary outcomes
overlap of symptoms in the initial phases suggests that early identification
overlap of symptoms in the initial phases suggests that early identification programmes should be aimed at detecting both the pre-psychotic and the pre-manic phases of schizophrenia and bipolar disorders.
Locations
Sponsors and contacts
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