Quantitative Ultrasound to Assess Steatotic Liver Disease in Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age9-18
SponsorUniversity of California, San Diego
About this trial
This research study is being conducted to find out more about advanced ultrasound techniques to non-invasively evaluate liver disease in children. The investigators are developing advanced techniques for analyzing ultrasound data and images of the liver, and they will compare it to other established methods used to evaluate the liver, including liver MRI.
The investigators plan to develop and test the advanced analysis techniques using conventional full-size ultrasound machines and, if possible, small handheld devices.
Our goals are:
* To assess the accuracy of the advanced ultrasound analysis techniques in children * To implement and assess these advanced technique on small handheld ultrasound devices, if possible
Eligibility criteria
Qualifiers
Age 9 to 18 years
Presence of risk factors for having MASLD
Ability and willingness of participant or legal guardian/parent to give written informed consent
Participant is willing to give written assent
Disqualifiers
Known liver disease other than MASLD
Pregnant or trying to become pregnant
Inability to undergo an MR study: weight exceeding scanner table limit, waist circumference > 140 cm, claustrophobie, and/or metal implants.
Trial design
Treatments tested in this trial
- MR exam
- US exam
- Blood draw
- Physical measurements
- Questionnaires
Treatment groups
120 Participants
are divided into 1 treatment groupSponsors and collaborators
University of California, San Diego
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Virginia Polytechnic Institute and State University
Collaborator
GE Healthcare
Collaborator
Source ClinicalTrials.gov