Quitting Matters Human Immunodeficiency Virus Hybrid Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWake Forest University Health Sciences

About this trial

The purpose of this study is to compare the advantages and disadvantages of two approaches for quitting smoking among people living with HIV (PWH). Participants will complete a 24- week (\~6-month) study where the Participants will be assigned to one of two smartphone apps to help with quitting smoking. Regardless of the group participants are assigned to, they will also receive a combination of nicotine replacement therapy (patches and gums) that have been shown to help people quit smoking. The main questions this study aims to answer are:

Participants will complete 5 video call visits over about 6 months. Participants will install their assigned smoking cessation app onto their phone and will be asked to use the app for the duration of the study along with their provided Nicotine Replacement Therapy (NRT) products. During the study visits, participants will meet with study staff to complete questionnaires and interviews. Participants may be asked to provide breath and saliva samples to measure the level of carbon monoxide and nicotine.

Eligibility criteria

Qualifiers

Self-reported daily cigarette smoking over the past 30 days

Self-reported HIV status

Age 18 or older

Desire to quit smoking

Disqualifiers

Current acute psychotic episode or unsafe to participate in the study

Pregnant or intending to become pregnant in the next 6 months

Currently receiving any pharmacological and/or behavioral intervention or counseling for smoking cessation

Any medical condition or medication that could compromise subject safety, as determined by the PIs and/or study physician

Trial design

Treatments tested in this trial

  • Learn to Quit-HIV (LTQ-H) App
  • QuitStart

Treatment groups

314 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor

University at Buffalo

Collaborator

National Institutes of Health (NIH)

Collaborator

National Cancer Institute (NCI)

Collaborator