Radiation-induced Toxicity of the Heart
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTechnische Universität Dresden
About this trial
Late side effects in radio(chemo)therapy \[R(CH)T\] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients with cancer in the thoracic region, risk stratification models for these toxicities are lacking. In this study, liquid, functional and imaging biomarkers are being investigated for their use in prediction of cardiac toxicity following R(CH)T for patients with thoracic malignancies.
Eligibility criteria
Qualifiers
Patients 18 years old or older
Patient's consent and written consent is available
Patients with the non-small cell lung cancer or esophageal cancer or breast cancer who have an indication for intended curative radio(chemo)therapy (in the case of breast cancer inclusion of female patients only)
Disqualifiers
Patients who are not capable of giving consent
Pregnant women
Patients with contraindications for MRI examinations (pacemakers, defibrillators, neurostimulators, aneurysm clips, cochlear implants, permanent make-up, metal splinters or osseosynthetic implants)
Patients with insufficient kidney function (glomerular filtration rate (GFR) of less than 30 ml/min)
Trial design
Treatments tested in this trial
- Imaging and biomarkers
Treatment groups
325 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov