Radiofrequency Denervation and Brain Imaging
ConditionLow Back Pain, Mechanical
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Aberdeen
About this trial
The goal of this observational study is to learn about changes in brain and its activity of following radiofrequency denervation treatment for chronic low back pain. The main question it aims to answer are:
* report the magnitude of the brain changes following radiofrequency treatment for low back pain. * identify changes unique to radiofrequency treatment
Patients with nociceptive type low back pain of moderate to severe intensity will be identified to undergo radiofrequency treatment. They will have 3 MRI scans - Baseline, after the diagnostic injections and 3 months after radiofrequency treatment. They will also fill questions relating to their pain, disability and health related quality of life.
Eligibility criteria
Qualifiers
Age 18 years or older
Chronic moderate to severe cLBP (defined by average pain intensity of ≥ 4 in the 11 point Numerical Pain rating scale and a minimum duration of 1 year)
Identified by clinical team as suitable for RFD pathway
Predominantly nociceptive pain (as defined by PainDetect score ≤12)
Disqualifiers
Any patient whose physical condition will preclude them from lying still for the duration of the brain scan.
Contraindication to magnetic resonance scanning such as an implantable cardiac device.
Women who are, or may be, pregnant. (Pregnant patients do not undergo pain procedures under radiological guidance as per routine clinical care)
Significant anxiety and depression (as defined by HADS score ≥ 9)
Trial design
Treatments tested in this trial
- MRI scan
Treatment groups
40 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Aberdeen
Lead sponsor
NHS Grampian
Collaborator
Source ClinicalTrials.gov