The present study aims to compare the efficacy (menstrual blood loss, pain, quality of life) and the safety (complications, recovery) of each conservative intervention (RFA, UAE) versus hysterectomy for the treatment of adenomyosis-related abnormal uterine bleeding, up to 2 years
Premenopausal women aged 30 to 50 years
Women who had at least 3 prior months failed medical therapy, or a contraindication to medical therapy, or refused medical therapy for adenomyosis-related AUB
Symptomatic pure internal adenomyosis or dominant adenomyosis (with less than 5 concurrent uterine fibroids type 3-7 < 5 cm) confirmed by MRI (< 6 months) according to ESHRE criteria
AUB defined as a PBAC score >100 at baseline
Uterine cavity abnormality or obstruction confirmed via imaging modalities or hysteroscopy
Deep infiltrating posterior subperitoneal endometriosis involving contiguous digestive tract structures
Uterine malignancy within the last five years
Secreting ovarian tumor
University Hospital, Bordeaux
Lead sponsor
French Ministry of Social Affairs and Health
Collaborator