This study will be held to overcome the previous limitations related to bone loss after teeth extraction by taking advantages from both Autogenous tooth graft and Simvastatin which will offer a promising synergistic approach for reducing alveolar ridge resorption, enhance bone regeneration and ensuring implant site development for future implant placement. This combination will address the gap in knowledge and offering a novel approach in alveolar ridge preservation. The Autogenous tooth graft will provide a scaffold and growth factor source for bone regeneration while Simvastatin will promotes osteogensis and angiogensis at graft site. So The goal of the present trial aims to evaluate the first-time application of Autogenous tooth graft from extracted tooth combined with Simvastatin with a ratio 1:1(test group) versus Autogenous tooth graft alone (control group) at an extraction socket of non molar single rooted teeth for alveolar ridge preservation and implant site development prior to implant placement.
The participants will be divided into two groups:
Intervention Group will receive Autogenous tooth graft combine with Simvastatin with a ratio 1:1 Control Group will receive Autogenous tooth graft. with follow up period 4 months.
Patients with badly broken, non-restorable, or periodontally hopeless non molar single rooted teeth.
Age from 20-45 years old(6,13). No sex predilection.
Medically free from any medical condition that would interfere with bone healing.
Patients with status classification (ASA I & II) with adequate oral hygiene condition.
Patients with any medical condition that contraindicated the procedure and general contraindications for Implant Surgery(6,13)
Patients who are allergic to Simvastatin drug.(6)
Presence of active infection around the tooth or remaining root.
Psychological reasons that might affect the procedure or the subsequent follow up visits.