Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Geneva
About this trial
The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated group. The predictive value of radiological tumor characteristics on hearing preservation and vestibular function will be also evaluated.
Additionally, the investigators will invite patients with vestibular Schwannoma to fill out questionnaires to assess their quality of life.
Eligibility criteria
Qualifiers
Aged 18 years or above
Patients with unilateral VS treated either with SRS or MRI-based observation strategy, as proposed by the institution's skull base tumor board independently of the study
Patients willing to take part in the study and give their informed consent
Disqualifiers
Previous surgical or radiation therapy for VS (including SRS)
Patients diagnosed with neurofibromatosis type II
Preexisting profound hearing loss, with a pure tone average (PTA) >90 and word recognition score (WRS) <10%, upon initial assessment
Previous middle ear surgery of the affected ear
Trial design
Treatments tested in this trial
- Stereotactic radiosurgery
Treatment groups
258 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov