Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNationwide Children's Hospital
About this trial
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing lower extremity revascularization procedures. We hypothesize that radiotracer imaging of the lower extremities will provide a sensitive non-invasive imaging tool for quantifying regional abnormalities in skeletal muscle perfusion and evaluating responses to medical treatment.
Eligibility criteria
Qualifiers
At least 18 years of age
Evidence of significant obstructive disease for one or multiple lower extremity arteries, as identified by prior ABI, TBI, CT angiography, ultrasound, or MR imaging.
Disqualifiers
Unable to give informed consent or follow-up
Pregnant or nursing
Under the age of 18
No history of peripheral artery disease
Trial design
Treatments tested in this trial
- SPECT/CT perfusion imaging
- PET/CT perfusion imaging
Treatment groups
192 Participants
are divided into 2 treatment groupsSponsors and collaborators
Nationwide Children's Hospital
Lead sponsor
Ohio State University
Collaborator
Source ClinicalTrials.gov