Health Trials

Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment of Middle Cerebral Artery

ConditionsEndovascular TherapyAcute Ischemic StrokeAcute Ischemic Stroke (AIS) Related to a Distal Occlusion
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-84
SponsorHyogo Medical University

About this trial

RESCUE-M2O trial is a prospective, open label, blinded endpoint (PROBE), two-arm, randomized, controlled, post-market study to assess the efficacy and safety of endovascular therapy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery.

Eligibility criteria

Qualifiers

Acute cerebral infarction

Aged 18-84 years

NIHSS score at admission ≥ 8

Prestroke mRS scores of 0-1 (able to carry out all usual activities)

Disqualifiers

Occlusion of the anterior temporal artery, duplicate M1, or accessory M1

Occlusion of multiple major intracranial arteries

Difficulty in endovascular access due to tortuous vascular anatomy

Significant mass effect with midline shift on CT (or MRI)

Trial design

Treatments tested in this trial

  • Endovascular therapy

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Hyogo Medical University

Lead sponsor

Source ClinicalTrials.gov