Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Bologna

About this trial

Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.

Eligibility criteria

Qualifiers

Male or female aged ≥ 18 years

TG>150 mg/dL

Subjects who have the capability to communicate and to comply with the study's requirements.

Subjects agree to participate in the study and having dated and signed the informed consent form.

Disqualifiers

Gluten hypersensitivity/Coeliac disease diagnosis

BMI>30 kg/m2

Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months

Any medical or surgical condition that would limit the patient adhesion to the study protocol.

Trial design

Treatments tested in this trial

  • Altograno® Bakery Foods
  • Standard Whole-Grain Bakery Foods

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators