From observational studies, it is know that the risk of developing colorectal cancer after polyp removal is lower if the patients adheres to surveillance recommendations. However, colonoscopy is burdensome for patients and colonoscopy availability is limited in many parts of the world. In addition, more than half of surveillance colonoscopies are without any findings. The trial investigates whether surveillance using fecal testing for blod is as good as colonoscopy after removal of colorectal polyps.
High-quality baseline colonoscopy with adequat cleansing and cecal intubation
Remocval of at least one advanced adenoma
Clean colon (all polyps removed)
Signed informed consent
Colorectal cancer
History of surgical colon resection for any reason
Genetic cancer syndrome (adenomatous or serrated polyposis syndrome; Lynch or Lynch-like syndrome)
≥ 10 adenomas at baseline colonoscopy (cumulative)
Sorlandet Hospital HF
Lead sponsor
Sykehuset Ostfold
Collaborator
University Hospital, Akershus
Collaborator
Vestre Viken Hospital Trust
Collaborator
Sykehuset Telemark Hospital Trust
Collaborator
Helse Møre og Romsdal HF
Collaborator
St. Olavs Hospital
Collaborator
University Hospital of North Norway
Collaborator
Sykehuset i Vestfold HF
Collaborator
Helse Stavanger HF
Collaborator
Turku University Hospital
Collaborator
Helsinki University Central Hospital
Collaborator
Randers Regional Hospital
Collaborator
Viborg Regional Hospital
Collaborator
Gødstrup Hospital
Collaborator
Horsens Hospital
Collaborator