Real-Time Dynamic Imaging Study of Normal Pharyngolaryngeal Structures During Barium Swallow (GLAM-III)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorZhejiang Cancer Hospital

About this trial

The integrity and functional stability of pharyngolaryngeal anatomical structures are critical for airway management, and the dynamic changes of key structures (e.g., pyriform sinus, cricoid cartilage lamina) during swallowing directly relate to the design and clinical safety of laryngeal masks. This observational study aims to investigate the real-time dynamic changes and physiological movement patterns of normal pharyngolaryngeal structures during barium swallow using routine barium meal examination imaging. The findings will provide anatomical and physiological evidence for optimizing laryngeal mask design and improving its anatomical fit with the pharynx and larynx.

Eligibility criteria

Qualifiers

Aged 18-75 years;

No history of pharyngolaryngeal surgery, trauma, or congenital malformation;

No swallowing dysfunction, pharyngolaryngeal inflammation, or neurological diseases affecting swallowing;

No recent use of drugs that affect muscle function (e.g., muscle relaxants, anticholinergics);

Disqualifiers

Presence of diseases that may compress pharyngolaryngeal structures (e.g., goiter, mediastinal mass);

Allergy to barium sulfate or other components of the barium suspension.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators