Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorBoston VA Research Institute, Inc.
About this trial
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.
Eligibility criteria
Qualifiers
patients diagnosed with SZ or schizoaffective disorder using DSM-5 criteria
auditory hallucinations not responsive to pharmacology as determined by chart review and a clinical interview of SCID.
Disqualifiers
neurologic illness
major head trauma
electroconvulsive therapy
alcohol or drug dependence
Trial design
Treatments tested in this trial
- stg-rt-fMRI-Neurofeeback
- sham-rt-fMRI-Neurofeedback
Treatment groups
104 Participants
are divided into 2 treatment groupsSponsors and collaborators
Boston VA Research Institute, Inc.
Lead sponsor
Mclean Hospital
Collaborator
Northeastern University
Collaborator
Cambridge Health Alliance
Collaborator
Source ClinicalTrials.gov