The aim of this study is to evaluate the efficacy of Eravacycline in the treatment of patients with bacterial infection and to assess the pharmacokinetics of Eravacycline and to establish a population pharmacokinetic model of Eravacycline.
Adult male or female aged 18-75 years
Not respond to initial empirical treatment, treatment time to reach Eravacycline steady-state concentration
Empirical antimicrobial treatment is ineffective
Eravacycline application for ≥ 3 days
Urinary tract infection
Allergic to Eravacycline, Tigecycline antibiotics or any excipients or have previously experienced serious adverse reactions
Any unstable or potentially endangering the safety of the subject and their compliance with the study as judged by the investigator; comorbidities or social circumstances that can make the subject unable to follow the study plan or even endanger the safety of the patient
Patients expected to survive for no longer than 48h.