Recording of Intraoperative Spinal Cord Stimulation and Monitoring

ConditionsCervical Stenosis Disk, Herniated Spondylosis

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorUniversity of California, Los Angeles

About this trial

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Eligibility criteria

Qualifiers

Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

Disqualifiers

none

Trial design

Treatments tested in this trial

epidural electrical stimulation

Treatment groups

150 Participants

are divided into 1 treatment group

Sponsors and collaborators

University of California, Los Angeles

Lead sponsor

Source ClinicalTrials.gov