Recovery of Physical Function After Critical Illness In Older Adults
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorUniversity of Kentucky
About this trial
The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially. Patients will be enrolled after life-saving modalities have been weaned near hospital discharge. Patients will participate in testing at baseline, 3-, 6-, 12-, and 24-months after hospital discharge. In a subset of patients (n = 18), muscle biopsies will be performed at baseline and then repeated once at either 12- or 24-months after hospital discharge.
Eligibility criteria
Qualifiers
adult patients (≥40 years of age)
patients who have survived an ICU admission of at least 72 hours
diagnosis of acute lung injury or sepsis are eligible.
Disqualifiers
individuals who were not ambulatory prior to ICU admission,
not expected to survive at least 6 months,
have a new or pre-existing brain infarct, injury, or neurological condition with deficits preventing participation in physical testing,
have a pre-existing geriatric syndrome that were confound recovery trajectory
Trial design
Treatments tested in this trial
- Not listed
Trial groups
150 Participants
are grouped into 1 trial groupSponsors and collaborators
Source ClinicalTrials.gov