Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients.

ConditionRectal Cancer
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSichuan Cancer Hospital and Research Institute

About this trial

Effect of ligation sequence of the inferior mesenteric artery and vein on circulating tumor cells and survival in laparoscopic rectal cancer surgery: a prospective, multicenter, randomized controlled study (ARVECTS)

Eligibility criteria

Qualifiers

Age: 18-75 years;

Histopathologically confirmed as rectal adenocarcinoma(tumor located within 15 cm from the anal verge at colonoscopy);

Patients with a stage I-III rectal cancer eligible for surgery and R0 resection is expected, patients with pelvic lateral lymph nodes metastasis are ineligible;

ECOG score: 0-1;

Disqualifiers

Patients who have received preoperative treatment (such as preoperative radiotherapy and chemotherapy);

Receiving transanal total mesorectal excision (taTME), specimen extraction through natural lumen (NOSES) ;

Recurrent rectal cancer;

Simultaneous or metachronous colorectal cancer;

Trial design

Treatments tested in this trial

  • Vein ligation first
  • Artery ligation first

Treatment groups

268 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Sichuan Cancer Hospital and Research Institute

Lead sponsor

Sichuan Provincial People's Hospital

Collaborator

The Second People's Hospital of Chengdu

Collaborator