About this trial
Effect of ligation sequence of the inferior mesenteric artery and vein on circulating tumor cells and survival in laparoscopic rectal cancer surgery: a prospective, multicenter, randomized controlled study (ARVECTS)
Eligibility criteria
Qualifiers
Age: 18-75 years;
Histopathologically confirmed as rectal adenocarcinoma(tumor located within 15 cm from the anal verge at colonoscopy);
Patients with a stage I-III rectal cancer eligible for surgery and R0 resection is expected, patients with pelvic lateral lymph nodes metastasis are ineligible;
ECOG score: 0-1;
Disqualifiers
Patients who have received preoperative treatment (such as preoperative radiotherapy and chemotherapy);
Receiving transanal total mesorectal excision (taTME), specimen extraction through natural lumen (NOSES) ;
Recurrent rectal cancer;
Simultaneous or metachronous colorectal cancer;
Trial design
Treatments tested in this trial
- Vein ligation first
- Artery ligation first
Treatment groups
Locations
Sponsors and collaborators
Sichuan Cancer Hospital and Research Institute
Lead sponsor
Sichuan Provincial People's Hospital
Collaborator
The Second People's Hospital of Chengdu
Collaborator