Reducing Blood Loss During Myomectomy:Uterine Artery Ligation Vs Pericervical Tourniquet

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age25-48
SponsorCairo University

About this trial

The goal of this clinical trial is to compare two surgical techniques for reducing blood loss during transabdominal myomectomy in women with symptomatic uterine fibroids. The main question it aims to answer is whether bilateral uterine artery ligation reduces intraoperative blood loss more effectively than pericervical mechanical tourniquet application, without increasing operative complications. Researchers will compare bilateral uterine artery ligation with pericervical mechanical tourniquet application during open myomectomy to evaluate blood loss and surgical safety. Participants will undergo elective transabdominal myomectomy and will be randomly assigned to one of the two vascular control techniques before myoma enucleation.

Eligibility criteria

Qualifiers

Female participants aged 25 to 48 years

Body mass index less than 35 kg/m²

Symptomatic uterine myomas requiring surgical treatment

Intramural myomas classified as FIGO types 3 to 6

Disqualifiers

Submucosal, intracavitary, pedunculated subserosal, cervical, or adnexal myomas

FIGO types 0, 1, 2, 7, or 8 myomas

History of pelvic inflammatory disease or peritonitis

Previous abdominal or pelvic surgery for non-obstetric causes

Trial design

Treatments tested in this trial

  • Bilateral Uterine Artery Ligation
  • Pericervical Mechanical Tourniquet Application

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Cairo University

Lead sponsor

Kafrelsheikh University

Collaborator