About this trial
The goal of this clinical trial is to compare two surgical techniques for reducing blood loss during transabdominal myomectomy in women with symptomatic uterine fibroids. The main question it aims to answer is whether bilateral uterine artery ligation reduces intraoperative blood loss more effectively than pericervical mechanical tourniquet application, without increasing operative complications. Researchers will compare bilateral uterine artery ligation with pericervical mechanical tourniquet application during open myomectomy to evaluate blood loss and surgical safety. Participants will undergo elective transabdominal myomectomy and will be randomly assigned to one of the two vascular control techniques before myoma enucleation.
Eligibility criteria
Qualifiers
Female participants aged 25 to 48 years
Body mass index less than 35 kg/m²
Symptomatic uterine myomas requiring surgical treatment
Intramural myomas classified as FIGO types 3 to 6
Disqualifiers
Submucosal, intracavitary, pedunculated subserosal, cervical, or adnexal myomas
FIGO types 0, 1, 2, 7, or 8 myomas
History of pelvic inflammatory disease or peritonitis
Previous abdominal or pelvic surgery for non-obstetric causes
Trial design
Treatments tested in this trial
- Bilateral Uterine Artery Ligation
- Pericervical Mechanical Tourniquet Application
Treatment groups
Sponsors and collaborators
Cairo University
Lead sponsor
Kafrelsheikh University
Collaborator