About this trial
The goal of this randomized-controlled trial (RCT) is to compare the effectiveness of the DREAMS-OT intervention with standard care in reducing post-Coronary Artery Bypass Graft (CABG) surgery delirium in patients undergoing CABG surgery.
The aims of the study are:
1. To determine if early and intensive OT will lower the incidence of post-op delirium in CABG patients compared to standard are. 2. To determine the cost effectiveness of the DREAMS-OT intervention.
The study team will compare intervention group and standard care group (control group) to see if there is a reduction in the incidence of delirium in patients 5 days post-CABG.
Eligibility criteria
Qualifiers
Patients deemed medically suitable for elective CABG surgery
Patients aged 21 years and above
Patients who are English or Mandarin speaking.
Patients who are able to provide consent
Disqualifiers
Patients who speak other languages are excluded due to the language requirements of certain outcome measures.
Patients with premorbid severe hearing impairment, severe cognitive impairment, progressive neurological disorders and psychological disorders will be excluded.
Patients with surgical complications resulting in profuse bleeding from any invasive sites, septic shock unresponsive to maximal treatment, and those who are moribund or have an expected mortality within 48 hours will be excluded.
Pregnant women will also be excluded from the study as well.
Trial design
Treatments tested in this trial
- DREAMS-OT
Treatment groups
Sponsors and collaborators
National University Hospital, Singapore
Lead sponsor
National University of Singapore
Collaborator
National Medical Research Council (NMRC), Singapore
Collaborator