About this trial
The investigators developed the Kisoboka ("It is possible") Intervention to address limitations of existing evidence-based interventions to optimize treatment as prevention among men living with HIV who drink alcohol at hazardous levels in "risk environments" such as fishing communities through reductions in hazardous alcohol use, improved adherence to HIV medications and achieving undetectable HIV viral loads.
Social and structural determinants unique to fishing communities interact to create a risk environment where hazardous drinking impedes adherence to HIV medications among men living with HIV, including prevalent social norms of drinking, drinking as a way of experiencing "reward" and connecting with others (e.g. in the context of transactional sex), stressful work conditions, a "live for today" outlook, and a cash-based economy with no traditional savings infrastructure leading to ease of daily expenditure on drinking and sex work. These social and environmental conditions result in high levels of alcohol misuse and HIV risk, poor HIV outcomes, and exacerbation of HIV-associated wellness comorbidities such as poor mental and subjective physical health and food insecurity.
The goal of this study is to learn if the intervention called Kisoboka works to help men in fishing communities reduce hazardous alcohol use, be better able to take the participants HIV medication as prescribed, and have undetectable HIV viral loads. The investigators will compare the Kisoboka intervention to a brief alcohol screening, adherence counseling, and referrals, and to components of the Kisoboka intervention.
Participants will attend intervention counseling sessions according to the study arm to which the participants are randomly assigned. The number of sessions ranges from 1 to 6 over 1 to 16 weeks and are individual only or both individual and group sessions.
Eligibility criteria
Qualifiers
living with HIV;
residing in a fishing community (on most days/nights);
AUDIT-C positive (≥4) indicating potential hazardous drinking;
>6 months since initial antiretroviral treatment (ART) initiation;
Disqualifiers
visibly intoxicated at enrollment (eligible to enroll when not intoxicated);
does not speak Luganda or English;
currently receiving a majority of work payments via mobile money/digital payments;
participated in the Kisoboka pilot RCT;
Trial design
Treatments tested in this trial
- Kisoboka
- Behavioral Economics
- Motivational Interviewing
- Screening and Referral
Treatment groups
Sponsors and collaborators
San Diego State University
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator
Makerere University Walter Reed Program
Collaborator
Makerere University
Collaborator