About this trial
The goal of this clinical trial is to learn about the molecular pathways associated with the benefit of a regular exercise program in patients with high blood pressure and who don't already participate in regular exercise.
The main question it aims to answer is to identify protein signatures associated with the benefits of a cardiac rehabilitation exercise program.
The trial will enroll 42 participants, who will be randomized to a 12 week cardiac rehabilitation exercise program versus control arm and asked to participate in the following at the beginning and end of study:
* Cardiopulmonary exercise test (CPET) * Echocardiogram * Physical function test * 6-minute walk test * Hand grip strength * Quality of life questionnaire * Blood draws
Researchers will compare results between those who do and don't participate in the exercise program.
Eligibility criteria
Qualifiers
Hypertension (controlled on stable medication regimen)
Structural heart abnormality (LVH or LA enlargement)
LVEF > 50%
Sedentary
Disqualifiers
Diabetes
Unable to exercise
Supplemental oxygen use
Pulmonary hypertension
Trial design
Treatments tested in this trial
- Cardiac Rehabilitation
- Attention Control