About this trial
This research study looks at the feasibility of using a new treatment, noninvasively activating the brain through repetitive transcranial magnetic stimulation (rTMS) to treat pain symptoms of complex regional pain syndrome (CRPS). This study will help us determine if this technique is feasible (able to recruit participants and if the research activities are feasible and can be used to treat CRPS patients with pain in a larger study. The investigators will also examine how TMS can be personalized to individuals using an individual's brain activity measured using EEG. The investigators will also study whether the effects of TMS are stronger if the TMS is delivered during a specific timing of the EEG activity.
Eligibility criteria
Qualifiers
Diagnosis of CRPS Type 1 affecting the upper or lower limb using the revised Budapest criteria
History of CRPS of at least 3 months since the start of symptoms or diagnosis
Disqualifiers
CRPS diagnosis greater than 3 years to avoid patients with chronic CRPS who may not respond to interventions
Contraindications to transcranial magnetic stimulation (TMS)
Known psychological diagnosis affecting comprehension
Prior experience with TMS
Trial design
Treatments tested in this trial
- Repetitive transcranial magnetic stimulation
Treatment groups
Sponsors and collaborators
McMaster University
Lead sponsor
Michael G. DeGroote Institute for Pain Research and Care (IPRC)
Collaborator