Reduction of Polypharmacy in Elderly People With Multiple Diseases

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age70+
SponsorMartin-Luther-Universität Halle-Wittenberg

About this trial

Elderly GP patients are often treated with five or more medications and therefore prone to adverse drug reactions (ADR). Potentially inappropriate prescriptions (PIPs) lead to increased adverse events like falls, hospitalizations and mortality. The primary aim of this study to reduce the frequency of ADRs in multimorbid patients aged 70 years and older by reducing polypharmacy.

Eligibility criteria

Qualifiers

≥ 5 longterm medications (> 6 months) (polypharmacy)

≥ 3 chronic diseases (multimorbidity)

≥ 1 family doctor consultation within the last 6 months

Disqualifiers

Patients with a critically reduced life expectancy

Patients who cannot autonomously visit the family practice

Patients who cannot participate in the informed consent process

Patients who are residing in a nursing home

Trial design

Treatments tested in this trial

  • Medication plan review
  • Adherence support

Treatment groups

1,146 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Martin-Luther-Universität Halle-Wittenberg

Lead sponsor

University of Leipzig

Collaborator

Hannover Medical School

Collaborator