Reframing Endometrial Physiology by Advanced Integrated Research

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorUniversity Hospital Southampton NHS Foundation Trust

About this trial

Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test. This research will use wearable sensors, magnetic resonance imaging (MRI) scans, and biological sample collection to identify changes in the uterus linked with HMB. The investigators aim to recruit approximately 130 participants across two study sites over three years, including people with and without HMB.

Eligibility criteria

Qualifiers

18-45

Having Periods

Disqualifiers

Currently pregnant or breastfeeding.

Known uterine malignancy, severe anaemia requiring urgent treatment, or other acute gynaecological emergencies.

Inability to undergo MRI (e.g., pacemaker, severe claustrophobia).

Inability to provide informed consent.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

100 Participants
are grouped into 2 trial groups

Sponsors and collaborators

University Hospital Southampton NHS Foundation Trust

Lead sponsor

University of Auckland, New Zealand

Collaborator