Refusal of Sentinel Lymph Node Biopsy in Patients With Luminal A Subtype Early Breast Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age60+
SponsorN.N. Petrov National Medical Research Center of Oncology

About this trial

Sentinel lymph node biopsy (SLNB) is the standard of axillary lymph node surgical staging in patients with early breast cancer.

The main goal of the study is to abandon axillary surgery in patients over 59 years old with early, luminal A, clinical lymph node negative breast cancer.

Eligibility criteria

Qualifiers

HER2-negative breast cancer (ER +/ PR +), Ki67 <= 30%, G1-2

age> 59 years.

morphologically confirmed diagnosis of breast cancer, IA-IIA stage

ECOG score 0-2.

Disqualifiers

Inconsistency with inclusion criteria.

stage T2-4, N1 or M1 cancer

severe uncontrolled concomitant chronic diseases or acute diseases

previous/concurrent malignancy or history of radiation therapy to the chest wall region

Trial design

Treatments tested in this trial

  • breast resection
  • Breast resection with sentinel lymph node biopsy

Treatment groups

100 Participants
are divided into 2 treatment groups