Patients with glial brain tumors have increasingly improved outcomes, with median survival of 5-15 years. However, the treatments, including surgery, radiation, and chemotherapy, often lead to impaired attention, working memory, and other cognitive functions. These cognitive deficits frequently have significant impact on patient quality of life. Although currently, there is no established standard of care to treat cognitive deficits in brain tumor patients, standard cognitive rehabilitative treatments have been developed for those with traumatic brain injury and stroke. However, the feasibility and efficacy of these cognitive treatments in individuals with brain tumors remains unclear.
Histologically confirmed low grade supratentorial primary brain tumor
>= 18 years old
Life expectancy > 12 weeks
Karnofsky performance status (KPS) >= 70
• Glioblastoma
• Extra-axial disease (i.e. meningioma)
• Infra-tentorial disease
Are not able to comply with study and/or follow-up procedures
6
Treatment groupsSee each treatment group below.
University of California, San Francisco
Lead sponsor
Tilburg University
Collaborator
University of California, Berkeley
Collaborator