Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorFederal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health

About this trial

Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (USN).

USN is observed in 24% of patients with left-hemispheric stroke and 45% of patients with right-hemispheric lesions in the acute phase acute phase and in 20% of patients in the chronic phase.

The presence of USN significantly complicates the rehabilitation process and negatively affects the functional outcomes. The complexity of USN correction is due to the heterogeneity of its manifestations and combination with other cognitive disorders. In 30-50% of patients with USN anosognosia is observed, in 60% - memory and attention disorders.

Traditional methods of rehabilitation lead to significant improvement in 30-50% of patients with USN. The use of combined methods of treatment, including pharmacotherapy and non-medication methods, can improve efficacy by up to 70-80%. This indicates the need to develop and investigate new approaches to correct USN.

Despite the growing number of studies in this area, there is still no unified approach to selecting the optimal method of USN correction for each individual patient.

Different methods of rehabilitation may have different effects on neuroplasticity processes, which opens new perspectives for optimization of rehabilitation strategies.

Eligibility criteria

Qualifiers

Normal cognitive development in accordance with age and educational level;

diagnosis with codes I63, I61 (ICD);

presence of unilateral spatial neglect syndrome in the neuropsychological status.

Disqualifiers

presence of mental and somatic pathology of severe degree and in decompensation stage;

the presence of gross oculomotor disorders;

presence of a sensory visual defect of moderate to severe severity

Trial design

Treatments tested in this trial

  • Conventional therapy
  • Eye tracking based therapy
  • Cognitive therapy

Treatment groups

30 Participants
are divided into 3 treatment groups