Rehabilitation Needs for Hematologic Cancer Candidate for Hematopoietic Stem Cell Transplantation or CAR T-Cell Therapy

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Modena and Reggio Emilia

About this trial

Hematopoietic Stem Cell Transplantation (HSCT) and CAR T-cell therapy are effective treatments for blood cancers, extending patients lives. However, these treatments can cause side effects like muscle weakness and fatigue. Recent findings suggest these issues can significantly affect patient quality of life during CAR T-cell therapy.

Patients undergoing HSCT and CAR T-cell therapy often face frequent infections and strong immune responses, requiring long periods of rest. This worsens their physical condition and impacts their quality of life, muscle strength, and fatigue levels. Minimizing these side effects is crucial to improve the well-being of patients undergoing these advanced treatments.

This study aims to assess the physical abilities (main goal) of patients preparing for HSCT or CAR T-cell therapy. It also aims to examine their quality of life and describe the symptoms and complications they may experience. The results will help identify rehabilitation needs for these patients.

Eligibility criteria

Qualifiers

Patients with hematologic cancer scheduled to undergo HSCT or CAR T-cell therapy;

Age ≥18 years

Able to provide informed consent to participate in the study

Able to understand and participate in the study

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

20 Participants
are grouped into 1 trial group

Sponsors and collaborators

University of Modena and Reggio Emilia

Lead sponsor

Azienda USL Reggio Emilia - IRCCS

Collaborator