Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60+
SponsorAzienda Ospedaliero-Universitaria Consorziale Policlinico di Bari

About this trial

The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity.

The main questions it aims to answer are:

Is glycemic control worse in diabetic patients with sarcopenic obesity? Are irisin levels higher in patients with non-sarcopenic obesity?

Participants will be asked to:

* Fill in three questionaries on lifestyle * Perform two physical performance tests

The investigators will collect the following data:

* Anthropometric measurements * Body composition by bioelectrical impedance analysis. * Results of routine blood analyses * Irisin levels by drawing a vial of blood from the antecubital vein

Eligibility criteria

Qualifiers

Diabetes mellitus type 2 diagnosed less than 10 years before

age >60 years

BMI (Body Mass Index) >30 kg/m2

eGFR (estimated Glomerular Filtration Rate) >30 ml/min

Disqualifiers

Insulin or insulin secretagogues use

Diabetes mellitus type 1, previous diabetic ketoacidosis

Neuromuscular diseases

Endocrinopathies that may cause myopathies (hypercortisolism, GH [growth hormone] deficiency, acromegaly, adrenal insufficiency, partial hypopituitarism or panhypopituitarism, male hypogonadism, hyperparathyroidism, hypoparathyroidism)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

120 Participants
are grouped into 2 trial groups