About this trial
This is a prospective, multicenter, observational study focusing on assessing and managing pain in patients with metastatic spinal tumors. Pain from spinal metastases adversely impacts quality of life, function, and treatment outcomes. Advances in surgical techniques have shown significant benefits. However, previous studies either lacked nuanced differentiations or simply categorized pain as mechanical or non-mechanical; explaining the highly variable pain outcome measurements in these studies. This study employs the AO Spine Cancer-Related Pain Classification to better categorize neoplastic spinal pain by etiology.
Eligibility criteria
Qualifiers
Age 18 years and older
Patients diagnosed with metastatic spinal tumors with one index metastatic site that, confirmed by the treating clinicians, is causing spine pain
Patients experience at least one type of pain that is of interest of this study, namely, axial non-triggered pain, axial triggered/mechanical pain, radicular non-triggered pain, and radicular triggered/mechanical pain
At least one type of the pain experienced has an NRS > 4 of 10
Disqualifiers
Estimated survival < 3 months
Patients with more than one symptomatic spine metastasis site
Patients with other sources of pain that may confound the measurement of the primary outcome
Patients undergoing the following treatments alone without the surgeries listed in the inclusion criteria or radiotherapy
Trial design
Treatments tested in this trial
- Surgery