Remote Ischemic Conditioning in Aneurysmal SAH
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAarhus University Hospital
About this trial
The goal of this clinical trial is to examine the effect of limb occlusion therapy (remote ischemic conditioning, RIC) in subjects with aneurysmal subarachnoid hemorrhage.
The main question it aims to answer is whether RIC can improve long-term recovery in participants with aneurysmal subarachnoid hemorrhage.
Researchers will compare levels of functional independence in participants in the RIC-group to participants in the sham-group.
Eligibility criteria
Qualifiers
Aneurysmal subarachnoid hemorrhage confirmed by computed tomography (CT) with aneurysm origin confirmed by computed tomography angiography (CTA) or digital subtraction angiography (DSA)
Aneurysmal subarachnoid hemorrhage symptom-onset ≤ 3 days
Aneurysm protected by clipping or coiling
Independent in daily living before symptom onset (mRS ≤ 2)
Disqualifiers
Subarachnoid hemorrhage caused by a lesion other than cerebral aneurysm
Symptomatic vasospasm at the time of enrollment
Previous cerebral lesion e.g. symptomatic cerebral infarction (>2cm), multiple sclerosis, symptomatic intracerebral hemorrhage, tumour, prior neurosurgery (excluding prior clipping or coiling of cold aneurysms without complications).
History of severe peripheral vascular disease or signs of severe peripheral vascular disease on physical examination
Trial design
Treatments tested in this trial
- Remote Ischemic Conditioning with Automatic Tourniquet Device
- Sham Remote Ischemic Conditioning with Automatic Tourniquet Device
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov