Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study)

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorPoliclinico Hospital

About this trial

This is a multicenter international observational prospective cohort study. The main questions it aims to answer are:

* PRIMARY AIM: To describe the capability of IRVF demodulation at diagnosis of ARDS to predict development of AKI within 7 days from the ARDS onset * SECONDARY AIMS: A)Describe the capability of IRVF demodulation or pattern of IRVF (continuous, pulsatility, biphasic, monophasic) to predict development of AKI within 14 days from the ARDS onset. B) To describe the RD parameters and VexUS in the AKI and no AKI patients over time. C) Describe the impact of invasive mechanical ventilation (IMV) on the intrarenal venous congestion and VexUS., D) Evaluation of effect of CRRT on IRVF pattern, VexUS and parameters. E) Describe the feasibility of renal doppler to assess IRVF in critically ill respiratory patients. F) Evaluate the incidence of AKD and CKD Participants will Adult patients with diagnosis of ARDS admitted to intensive care unit and undergoing invasive mechanical ventilation

Eligibility criteria

Qualifiers

Age > 18 years

Critically ill patients admitted to intensive care unit with a diagnosis of ARDS according to Berlino criteria

Beginning of IMV less than 48 hours or Clinical decision to begin IMV.

Life expectancy > 24 hours

Disqualifiers

AKI prior to the onset of ARDS

Chronic respiratory failure due to chronic respiratory diseases

Chronic renal disease (CKD stage ≥ 2) and any ureteral obstruction. Definition of CKD patient is according to the latest guideline KDIGO

Chronic Heart Failure

Trial design

Treatments tested in this trial

  • ARDS+AKI

Treatment groups

No treatment groups listed

Locations

This trial has no locations

Sponsors and collaborators