Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-18
SponsorBeni-Suef University
About this trial
Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children. Although open pyeloplasty is an effective standard treatment, the degree of postoperative renal functional recovery varies between patients.
This prospective observational cohort study will evaluate whether renal cortical shear wave elastography can predict renal functional recovery after open pyeloplasty in children with unilateral primary ureteropelvic junction obstruction. Renal cortical shear wave elastography will be assessed before surgery and during follow-up, and the change in elastography values will be compared with renal isotope findings after surgery.
The primary objective is to evaluate the predictive value of the change in renal cortical shear wave elastography from baseline to 3 months after surgery for isotope-defined renal functional recovery at 6 months after open pyeloplasty.
Eligibility criteria
Qualifiers
Children aged 6 months to 18 years.
Diagnosis of unilateral primary ureteropelvic junction obstruction.
Planned for open dismembered pyeloplasty.
Availability of preoperative renal ultrasonography, renal cortical shear wave elastography, and diuretic renography.
Disqualifiers
Bilateral ureteropelvic junction obstruction.
Secondary ureteropelvic junction obstruction.
Previous ipsilateral upper urinary tract surgery.
Associated major urinary tract anomalies likely to independently affect renal function, including vesicoureteral reflux, megaureter, duplex system, posterior urethral valves, or ectopic kidney.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
84 Participants
are grouped into 1 trial groupSponsors and collaborators
Source ClinicalTrials.gov