Repetitive Transcranial Magnetic Stimulation Paired with Augmented Reality to Alter Concussion Symptoms
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMcMaster University
About this trial
This study aims to determine whether the delivery of brain stimulation paired with a balance training task can improve symptoms of dizziness for individuals experiencing these symptoms due to concussion. The main questions it aims to answer are:
* Does repetitive transcranial magnetic stimulation (rTMS) paired with balance training improve the symptoms of dizziness in individuals with persistent dizziness due to concussion? * Is the proposed rTMS and balance training protocol feasible in this population?
Researchers will compare results from a sham rTMS group with those from a real rTMS group to see if any observed changes are from the placebo effect rather than the expected effects of real rTMS.
Participants will receive pulses of rTMS to the area of the brain responsible for control of movement and then be asked to interact with digital objects using augmented reality glasses for 14 days over 3 weeks.
Eligibility criteria
Qualifiers
Male or female aged 18-65 years
Diagnosis of mTBI according to the American Congress of Rehabilitation Medicine Diagnostic Criteria (Silverberg et al., 2023). All participants have diagnosis confirmed with Dr. Rathbone before enrollment.
Persistent dizziness beyond 3-months following the initial head injury.
Comprehension of spoken and written English language or have a language interpreter present for all study visits.
Disqualifiers
History of chronic dizziness unrelated to concussive events.
Contraindications to TMS: presence of pacemaker, metal/electrical/magnetic implants not including titanium, known history of untreated or uncontrolled psychological disorders, pregnancy, history of seizure or diagnoses of epilepsy, taking medications that increase the risk of seizure.
Inability to continue current medical therapies for the duration of the study.
If imaging was done at the time of injury, individuals with a positive CT head will be excluded from the study
Trial design
Treatments tested in this trial
- Repetitive transcranial magnetic stimulation
- Augmented reality vestibular rehabilitation therapy
- SHAM repetitive transcranial magnetic stimulation
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
McMaster University
Lead sponsor
Greenbank Concussion Clinic
Collaborator
Source ClinicalTrials.gov