This is an interventional, multicenter, prospective study involving healthy volunteers, to primarily assess the reproducibility of multiparametric renal MRI on 1.5T scanners. The study is also aimed at assessing possible differences in renal MRI reproducibility on 1.5T MRI scanners by sex and age, and assessing possible differences in renal MRI reproducibility across field strengths (1.5T vs 3T) in the subgroup of subjects enrolled in both RESPECT clinical study and in the current subproject.
Provision of written informed consent prior to any study specific procedures
Male and female subjects aged [18-70] years
Office SBP values < 140 mmHg and DBP values ≤ 90 mmHg, under no antihypertensive therapy
Normal renal function defined as: estimated glomerular filtration rate [eGFR] ≥ 60mL/min/1.73m2 (using CKD-EPI Creatinine Equation)
Previous enrollment in the present substudy
Contraindications to MRI including caustrophobia, pregnancy, cardiac pacemakers or other MRI-incompatible prostheses
Ongoing therapy (e.g. for diabetes, dyslipidemia, or any acute disease)
Past or current oncological pathology