About this trial
Mining AIS biomarkers, elucidating the new mechanism of AIS pathogenicity, constructing risk prediction models, optimizing AIS precise diagnosis and treatment techniques, formulating precise diagnosis and treatment protocols and technical specifications for AIS combined with Chinese and Western medicine with independent intellectual property rights, and realizing the full coverage of Zhejiang Province by the end of 2026, so as to form the "Zhejiang experience" of AIS diagnosis and treatment.
Eligibility criteria
Qualifiers
Patients diagnosed with AIS;② Sex is not limited, age 10-18 years old; ③ Those who sign the informed consent and can cooperate with follow-up visits; ④ Those who can cooperate with X-ray, chemical test, genetic test and other examination and evaluation for the measurement of relevant indexes.
Disqualifiers
Subjects with spine-related diseases such as Marfan's syndrome;
Subjects with previous ankylosing spondylitis, spinal neurofibroma, spinal tuberculosis, spinal trauma and other spine-related diseases;
Subjects with combined serious medical diseases and psychiatric patients;
Those with ECOG score > 2, which may have an impact on the study results;
Trial design
Treatments tested in this trial
- Low risk experimental group
- Medium risk experimental group
- High risk experimental group
- Control group COBB 10-20°
- Control group COBB 20-45°
- Control group COBB >45°
- Experimental group (AIS group)
- Control group (healthy control)
- Controlled follow-up before and after AIS